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AVID 100

Drug Profile

AVID 100

Alternative Names: AVID-100

Latest Information Update: 31 Oct 2021

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At a glance

  • Originator Formation Biologics
  • Developer Forbius; National Research Council Canada
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates; Immunotherapies; Immunotoxins; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Mitosis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer; Squamous cell cancer; Triple negative breast cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 30 Jan 2021 Formation Biologics terminated the phase Ia/IIa trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) due to lack of efficacy (NCT03094169)
  • 21 Sep 2020 Forbius has been acquired by Bristol-Myers Squibb
  • 26 Oct 2019 Efficacy data from a phase Ia/IIa trial in Solid tumours presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2019)
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