ISIS 702843

Drug Profile

ISIS 702843

Alternative Names: IONIS TMPRSS6-Lrx; ISIS-702843

Latest Information Update: 08 Jun 2017

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At a glance

  • Originator Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action TMPRSS6 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Thalassaemia

Most Recent Events

  • 06 Jun 2017 Phase-I clinical trials in Thalassaemia (In volunteers) in Australia (SC) (NCT03165864)
  • 31 Mar 2017 Ionis Pharmaceuticals and INC Research Australia plan a phase I trial in Healthy volunteers in Australia and USA (SC, Injection) (1056098; ACTRN12617000458336p)
  • 30 Mar 2017 Preclinical trials in Thalassaemia in Australia, USA (SC), before March 2017
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