Drug Profile


Alternative Names: VRC01 mRNA-LNP

Latest Information Update: 06 Apr 2017

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At a glance

  • Originator Acuitas Therapeutics
  • Developer Acuitas Therapeutics; University of Pennsylvania
  • Class Antiretrovirals; Monoclonal antibodies; RNA
  • Mechanism of Action Gene transference; HIV antigen inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical HIV-1 infections

Most Recent Events

  • 06 Apr 2017 Preclinical trials in HIV-1 infections in Canada, USA (Injection) before April 2017
  • 02 Mar 2017 Preclinical data in HIV-1 infections released by Acuitas Therapeutics and the University of Pennsylvania
  • 01 Dec 2013 Arbutus Biopharma enters into a cross-license agreement with Acuitas Therapeutics for the former's lipid nanoparticle (LNP) technology
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