IT 141

Drug Profile

IT 141

Alternative Names: IT-141; SN 38; SN-38 nanoparticles - Intezyne Technologies

Latest Information Update: 12 Apr 2017

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At a glance

  • Originator Intezyne
  • Class Alkaloids; Anthracyclines; Antineoplastics; Camptothecins; Gene therapies; Small molecules
  • Mechanism of Action Apoptosis stimulants; DNA topoisomerase I inhibitors; Gene transference; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 12 Apr 2017 Chemical structure information added
  • 23 Mar 2017 Phase-I clinical trials in Solid tumours (Monotherapy, Recurrent, Late-stage disease) in USA (IV) (NCT03096340)
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