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SPH 3127

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Drug Profile

SPH 3127

Alternative Names: I-001; I001-A; I001-B; SPH-3127

Latest Information Update: 03 Jul 2023

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation; Shanghai Pharmaceuticals Holding
  • Developer Shanghai Pharmaceuticals Holding
  • Class Anti-inflammatories; Antihypertensives; Small molecules
  • Mechanism of Action Renin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypertension
  • Phase II Diabetic nephropathies; Ulcerative colitis

Most Recent Events

  • 19 Jun 2023 Phase-II clinical trials in Ulcerative colitis in China (PO) (NCT05770609)
  • 14 Dec 2022 Shanghai Pharmaceuticals Holding completes a phase I/II trial in Hypertension (In volunteers) in China (NCT05593562)
  • 16 Oct 2022 Shanghai Pharmaceuticals Holding initiates enrolment in a phase I/II trial for Hypertension in China (NCT05593562)
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