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Sisunatovir - ReViral

Drug Profile

Sisunatovir - ReViral

Alternative Names: PF-07923568; RV-521; RV521.HCl; Sisunatovir hydrochloride - ReViral

Latest Information Update: 03 Apr 2024

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At a glance

  • Originator ReViral
  • Developer Pfizer; ReViral
  • Class Antivirals; Benzimidazoles; Cyclopropanes; Fluorinated hydrocarbons; Indoles; Small molecules
  • Mechanism of Action Viral fusion protein inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Respiratory syncytial virus infections
  • Phase I Renal failure

Most Recent Events

  • 26 Feb 2024 Pfizer completes a phase I trials in Respiratory syncytial virus infections (In volunteers, In the elderly, In adults) in Belgium (PO) (NCT05994963) (EudraCT2023-505228-79-00)
  • 08 Feb 2024 Sisunatovir - ReViral receives Fast Track designation for Respiratory syncytial virus infections [PO] in USA prior to February 2024 (Pfizer pipeline, February 2024)
  • 07 Feb 2024 Pfizer completes a phase I pharmacokinetics trial (In volunteers) in USA (PO, Capsule) (NCT05857644)
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