SAGE 718

Drug Profile

SAGE 718

Alternative Names: SAGE-718

Latest Information Update: 08 Nov 2017

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At a glance

  • Originator SAGE Therapeutics
  • Class Small molecules
  • Mechanism of Action NMDA receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Smith-Lemli-Opitz syndrome
  • Preclinical Encephalitis

Most Recent Events

  • 02 Nov 2017 Adverse events and pharmacokinetics data from a phase I trial in Smith-Lemli-Opitz syndrome released by Sage Therapeutics
  • 02 Nov 2017 Sage Therapeutics completes a phase I trial in Smith-Lemli-Opitz syndrome (PO)
  • 27 Apr 2017 Phase-I clinical trials in Smith-Lemli-Opitz syndrome (In volunteers) in USA (PO)
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