Melanoma-associated antigen A4-specific T-cells - Adaptimmune

Drug Profile

Melanoma-associated antigen A4-specific T-cells - Adaptimmune

Alternative Names: MAGE-A4 SPEAR T-cell therapy; MAGE-A4-SPEAR-T-cell-therapy-Adaptimmune; MAGE-A4ᶜ¹º³²T

Latest Information Update: 01 Jun 2017

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At a glance

  • Originator Adaptimmune
  • Class Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunostimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 15 May 2017 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable; Metastatic disease, Late-stage disease) in USA (IV) (NCT03132922)
  • 13 Mar 2017 Adaptimmune Therapeutics has patents pending for MAGE-A4 SPEAR T-cell therapy in United Kingdom
  • 09 Jan 2017 US FDA approves IND application for MAGE-A4 SPEAR T-cell therapy in Solid tumours (malignant)
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