Research programme : Purinergic P1 receptor modulators - Lewis and Clark Pharmaceuticals

Drug Profile

Research programme : Purinergic P1 receptor modulators - Lewis and Clark Pharmaceuticals

Alternative Names: Adenosine receptor modulators - Lewis and Clark Pharmaceuticals

Latest Information Update: 28 Oct 2017

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At a glance

  • Originator Lewis and Clark Pharmaceuticals
  • Developer Lewis and Clark Pharmaceuticals; National Institutes of Health (USA)
  • Class Anti-inflammatories; Antiasthmatics; Antibacterials; Antiglaucomas; Antineoplastics
  • Mechanism of Action Adenosine A2A receptor agonists; Adenosine A2A receptor antagonists; Adenosine A2B receptor antagonists; Purinergic P1 receptor modulators; Purinergic receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Asthma; Atherosclerosis; Autoimmune disorders; Cancer; Clostridium infections; Fatty liver; Glaucoma; Graft-versus-host disease; Inflammation; Pain

Most Recent Events

  • 23 Oct 2017 Inspyr Therapeutics and National Institutes of Health (USA) enter into research collaboration to evaluate adenosine receptor modulators for prevention of Graft versus host disease
  • 23 Oct 2017 Preclinical trials in Graft-versus-host disease (Prevention) in USA (unspecified route)
  • 02 Oct 2017 Inspyr Therapeutics enters into a research collaboration agreement with University of Virginia School of Medicine
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