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UCART 123

Drug Profile

UCART 123

Alternative Names: Anti-CD123 CAR-T Cells-Cellectis; UCART-123; UCART-123v1.2

Latest Information Update: 15 Dec 2022

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At a glance

  • Originator Cellectis
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Acute myeloid leukaemia
  • No development reported Blastic plasmacytoid dendritic cell neoplasm

Most Recent Events

  • 13 Dec 2022 Updated efficacy, adverse events and pharmacokinetics data from the phase I AMELI-01 trial in Acute myeloid leukemia presented at the 64th Annual Meeting of the American Society of Hematology (ASH-Hem-2022)
  • 05 Dec 2022 UCART 123 is still in phase I AMELI-01 trial for Acute myeloid leukemia (Second line therapy or greater) in USA (IV, Infusion) (NCT03190278)
  • 28 Nov 2022 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Second-line therapy or greater) in USA (IV, Infusion)
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