AZD 4785

Drug Profile

AZD 4785

Alternative Names: AZD-4785; IONIS-KRAS-2.5Rx

Latest Information Update: 20 Aug 2017

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer AstraZeneca; Ionis Pharmaceuticals
  • Class Antineoplastics; Antisense oligonucleotides; Nucleotides
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 14 Jun 2017 Pharmacodynamics and adverse events data in Non-small cell lung cancer released by AstraZeneca
  • 15 May 2017 Phase-I clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease) in USA (IV) (NCT03101839)
  • 15 May 2017 Phase-I clinical trials in Solid tumours (Late- stage disease, Metastatic disease) in USA (IV) (NCT03101839)
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