Drug Profile


Alternative Names: IONIS-FB-LRx

Latest Information Update: 28 Aug 2017

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At a glance

  • Originator Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action Complement-Factor-B-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Age-related macular degeneration

Most Recent Events

  • 11 Aug 2017 Ionis Pharmaceuticals plans a phase II trial for Age-related macular degeneration in USA
  • 11 Aug 2017 GlaxoSmithKline declines option to license IONIS FB LRx
  • 11 Aug 2017 Pharmacokinetics data from a phase I trial in Age-related macular degeneration released by Ionis Pharmaceuticals
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