MGD 013

Drug Profile

MGD 013

Alternative Names: Anti-LAG-3 bispecific DART protein; Anti-PD-1; MGD013; PD-1 X LAG-3; PD-1 x LAG-3 bispecific DART molecule

Latest Information Update: 24 Aug 2017

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At a glance

  • Originator MacroGenics
  • Class Antineoplastics; Bispecific antibodies; Proteins
  • Mechanism of Action CD223 antigen inhibitors; PDCD 1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Haematological malignancies; Solid tumours

Most Recent Events

  • 01 Aug 2017 Phase-I clinical trials in Haematological malignancies (Inoperable/Unresectable, Metastatic disease) in USA (IV) (NCT03219268)
  • 01 Aug 2017 Phase-I clinical trials in Solid tumours (Late-stage disease, Inoperable/Unresectable, Metastatic disease) in USA (IV) (NCT03219268)
  • 03 May 2017 MacroGenics files an IND application for Cancer
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