CAN 04

Drug Profile

CAN 04

Alternative Names: CAN04

Latest Information Update: 08 Jan 2018

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At a glance

  • Originator Lund University
  • Developer Cantargia
  • Class Anti-inflammatories; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Interleukin-1 receptor accessory protein inhibitors; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Breast cancer; Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer
  • Preclinical Solid tumours

Most Recent Events

  • 05 Jan 2018 Cantargia receives patent allowance for IL1RAP-targeting antibodies in China
  • 04 Jan 2018 Cantargia receives patent allowance for IL1RAP-targeting antibodies in USA
  • 13 Oct 2017 Phase-I/II clinical trials in Breast cancer (Late-stage disease, Metastatic disease, Combination therapy, Second-line therapy or greater) in Denmark, Norway, Belgium and Netherlands (IV) (NCT03267316)
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