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Campath [Alemtuzumab] Dose Escalation, Low-Dose TBI and Fludarabine Followed by HLA Class II Mismatched Donor Stem Cell Transplantation for Patients With Hematologic Malignancies - A Multi-Center Trial.

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Trial Profile

Campath [Alemtuzumab] Dose Escalation, Low-Dose TBI and Fludarabine Followed by HLA Class II Mismatched Donor Stem Cell Transplantation for Patients With Hematologic Malignancies - A Multi-Center Trial.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Apr 2022

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At a glance

  • Drugs Alemtuzumab (Primary) ; Ciclosporin; Ciclosporin; Fludarabine; Mycophenolate mofetil
  • Indications Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Chronic myeloid leukaemia; Diffuse large B cell lymphoma; Graft-versus-host disease; Hodgkin's disease; Mantle-cell lymphoma; Multiple myeloma; Myelodysplastic syndromes; Myeloproliferative disorders; Non-Hodgkin's lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions

    • Most Recent Events

    • 15 Jan 2020 Status changed from active, no longer recruiting to completed.
    • 16 Aug 2011 Planned end date changed from 1 Dec 2012 to 1 Dec 2013 as reported by ClinicalTrials.gov.
    • 04 Aug 2011 Additional lead trial centre identified as reported by ClinicalTrials.gov.
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