A Phase I, Sequential Cohort, Dose Escalation Trial to Determine the Safety, Tolerability, and Maximum Tolerated Dose of Daily x 5 Administration of AP23573, an mTOR Inhibitor, in Patients With Refractory or Advanced Malignancies.

Trial Profile

A Phase I, Sequential Cohort, Dose Escalation Trial to Determine the Safety, Tolerability, and Maximum Tolerated Dose of Daily x 5 Administration of AP23573, an mTOR Inhibitor, in Patients With Refractory or Advanced Malignancies.

Completed
Phase of Trial: Phase I

Latest Information Update: 07 Mar 2014

At a glance

  • Drugs Ridaforolimus (Primary)
  • Indications Lymphoma; Myeloma
  • Focus Adverse reactions
  • Sponsors Merck Sharp & Dohme
  • Most Recent Events

    • 02 Jun 2010 Merck and Co added as trial sponsor, trial affiliate and Merck Sharp and Dohme added as trial affiliate, lead trial centres as reported by ClinicalTrials.gov.
    • 12 May 2009 Additional lead trial investigator identified as reported by ClinicalTrials.gov.
    • 12 May 2009 Actual end date (Feb 2009) added as reported by ClinicalTrials.gov.
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