An open label pilot study of induction therapy with a single high dose bolus of intravenous methotrexate with leucovorin rescue, prior to initiation of AVONEX [interferon-beta-1a] treatment, in patients presenting with a first acute demyelinating event: comparison with CHAMPS results

Trial Profile

An open label pilot study of induction therapy with a single high dose bolus of intravenous methotrexate with leucovorin rescue, prior to initiation of AVONEX [interferon-beta-1a] treatment, in patients presenting with a first acute demyelinating event: comparison with CHAMPS results

Withdrawn prior to enrolment
Phase of Trial: Phase IV

Latest Information Update: 25 Sep 2015

At a glance

  • Drugs Interferon beta-1a (Primary) ; Methotrexate; Methylprednisolone
  • Indications Multiple sclerosis
  • Focus Therapeutic Use
  • Most Recent Events

    • 03 Feb 2010 Additional lead trial centre identified as reported by ClinicalTrials.gov.
    • 17 Dec 2009 Status changed from not yet recruiting to withdrawn prior to recruitment as reported by ClinicalTrials.gov.
    • 06 Oct 2005 New trial record.
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