A randomized, double-Blind, placebo-controlled, parallel-group, multicenter study to determine the safety and efficacy of natalizumab, when added to Avonex (interferon beta-1a), in subjects with relapsing-remitting multiple sclerosis

Trial Profile

A randomized, double-Blind, placebo-controlled, parallel-group, multicenter study to determine the safety and efficacy of natalizumab, when added to Avonex (interferon beta-1a), in subjects with relapsing-remitting multiple sclerosis

Completed
Phase of Trial: Phase III

Latest Information Update: 17 Sep 2016

At a glance

  • Drugs Natalizumab (Primary) ; Interferon beta-1a
  • Indications Multiple sclerosis
  • Focus Registrational; Therapeutic Use
  • Acronyms SENTINEL
  • Sponsors Biogen
  • Most Recent Events

    • 17 Sep 2016 Results of this and other four trials assessing relationship of natalizumab exposure and MRI response presented at the 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
    • 16 Apr 2008 Patient analysis presented at the 60th Annual Meeting of the American Academy of Neurology.
    • 10 Oct 2005 New trial record.
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