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A phase IIIB, multi-center, randomized, double-blind, placebo-controlled comparative study of abatacept or infliximab in combination with methotrexate in controlling disease activity in subjects with rheumatoid arthritis having an inadequate clinical response to methotrexate

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Trial Profile

A phase IIIB, multi-center, randomized, double-blind, placebo-controlled comparative study of abatacept or infliximab in combination with methotrexate in controlling disease activity in subjects with rheumatoid arthritis having an inadequate clinical response to methotrexate

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Oct 2021

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At a glance

  • Drugs Abatacept (Primary) ; Infliximab; Methotrexate
  • Indications Rheumatoid arthritis
  • Focus Adverse reactions; Pharmacodynamics; Pharmacogenomic; Registrational; Therapeutic Use
  • Acronyms ATTEST
  • Sponsors Bristol-Myers Squibb

    • Most Recent Events

    • 12 Aug 2018 Results from AMPLE and ATTEST trials published in the Clinical and Experimental Rheumatology
    • 07 Nov 2012 Planned number of patients changed from 400 to 675 as reported by European Clinical Trials Database record
    • 04 Oct 2011 Results presented at the 75th Annual Scientific Meeting of the American College of Rheumatology and the 46th Annual Meeting of the Association of Rheumatology and Health Professionals.
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