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A phase III randomized, open-label study of CG1940 and CG8711 [cancer vaccine-GVAX] versus docetaxel [Taxotere] and prednisone in patients with metastatic hormone-refractory prostate cancer who are chemotherapy-naive

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Trial Profile

A phase III randomized, open-label study of CG1940 and CG8711 [cancer vaccine-GVAX] versus docetaxel [Taxotere] and prednisone in patients with metastatic hormone-refractory prostate cancer who are chemotherapy-naive

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 09 Sep 2016

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At a glance

  • Drugs Docetaxel (Primary) ; Prednisone (Primary) ; Tumour cell vaccine-GVAX (Primary)
  • Indications Prostate cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms VITAL-1

    • Most Recent Events

    • 28 Feb 2009 Final results were presented at the ASCO 2009 Genitourinary Cancers Symposium.
    • 17 Oct 2008 Status changed from active, no longer recruiting to discontinued (Independent Data Monitoring Committee showed that the trial had less than 30% chance of meeting its primary endpoint).
    • 29 Sep 2008 Checked against clinicltrials.gov record.
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