A phase I dose-finding study and a randomized phase II study of Alimta [pemetrexed] plus oxaliplatin versus oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4 regimen) in the first-line treatment of patients with locally advanced unresectable or stage IV colorectal cancer.

Trial Profile

A phase I dose-finding study and a randomized phase II study of Alimta [pemetrexed] plus oxaliplatin versus oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4 regimen) in the first-line treatment of patients with locally advanced unresectable or stage IV colorectal cancer.

Completed
Phase of Trial: Phase I/II

Latest Information Update: 11 Mar 2011

At a glance

  • Drugs Fluorouracil; Folinic acid; Oxaliplatin; Pemetrexed
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 11 Mar 2011 Status changed from suspended to completed as reported by ClinicalTrials.gov.
    • 02 Nov 2005 New trial record.
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