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5-Fluorouracil/folinate/oxaliplatin (Eloxatin) (FLOX [FOLFOX] regimen), given continuously or intermittently, in combination with cetuximab (Erbitux), in first-line treatment of metastatic colorectal cancer. A phase III multicenter trial.

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Trial Profile

5-Fluorouracil/folinate/oxaliplatin (Eloxatin) (FLOX [FOLFOX] regimen), given continuously or intermittently, in combination with cetuximab (Erbitux), in first-line treatment of metastatic colorectal cancer. A phase III multicenter trial.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Nov 2021

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At a glance

  • Drugs Cetuximab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Biomarker; Therapeutic Use
  • Acronyms Nordic-VII

    • Most Recent Events

    • 21 Sep 2020 Results of meta analysis validating the efficacy and safety between Q2W vs. Q1W CET dosing presented at the 45th European Society for Medical Oncology Congress
    • 01 Aug 2017 Results evaluating the effect of cetuximab on health-related quality of life (HRQoL) in the NORDIC-VII trial on metastatic colorectal cancer (mCRC), published in the European Journal of Cancer.
    • 11 Apr 2017 Results of final survival analyses and extended RAS data published in the British Journal of Cancer.
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