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A double-blind, randomized, placebo-controlled multi-center, phase II parallel dose-ranging study to assess the antifibrotic activity of GI262570 [farglitazar] in chronic hepatitis C subjects with hepatic fibrosis who have failed prior antiviral therapy

Trial Profile

A double-blind, randomized, placebo-controlled multi-center, phase II parallel dose-ranging study to assess the antifibrotic activity of GI262570 [farglitazar] in chronic hepatitis C subjects with hepatic fibrosis who have failed prior antiviral therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Sep 2023

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At a glance

  • Drugs Farglitazar (Primary)
  • Indications Hepatitis C
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK
  • Most Recent Events

    • 15 Nov 2021 Results of an association between CTX-III and fibrotic resolution and shift in type III collagen remodeling as a function of fibrosis stage analysis presented at The Liver Meeting 2021: 72nd Annual Meeting of the American Association for the Study of Liver Diseases
    • 26 Jun 2021 Results(n=127) predicting response to antifibrotic treatment, with a peroxisome proliferator activated receptor -y agonist, in patients with chronic hepatitis C presented at The International Liver Congress 2021
    • 23 May 2021 Results (n=46) assessing association between CTX-III and fibrotic resolution and shift in type III collagen remodeling as a function of fibrosis stagepresented at the Digestive Disease Week 2021
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