A Randomized, Multicenter Phase 3 Study to Compare the Efficacy of Panitumumab in Combination With Chemotherapy to the Efficacy of Chemotherapy Alone in Patients With Previously Treated Metastatic Colorectal Cancer.

Trial Profile

A Randomized, Multicenter Phase 3 Study to Compare the Efficacy of Panitumumab in Combination With Chemotherapy to the Efficacy of Chemotherapy Alone in Patients With Previously Treated Metastatic Colorectal Cancer.

Completed
Phase of Trial: Phase III

Latest Information Update: 12 Sep 2017

At a glance

  • Drugs Panitumumab (Primary) ; Fluorouracil; Folinic acid; Irinotecan
  • Indications Colorectal cancer
  • Focus Pharmacogenomic; Registrational; Therapeutic Use
  • Sponsors Amgen
  • Most Recent Events

    • 12 Sep 2017 Secondary pooled analysis of data from two clinical trials (NCT00339183 and NCT00364013) presented at the 42nd European Society for Medical Oncology Congress.
    • 11 Oct 2016 Results from NCT00339183 and NCT00364013 studies evaluating the association of dermatologic toxicity severity with patient characteristics/laboratory values and treatment outcomes, presented at the 41st European Society for Medical Oncology Congress.
    • 11 Oct 2016 Results of retrospective analysis of three trials (NCT00364013, NCT00819780, NCT00339183) assessing outcomes in relation to location of the primary tumor were presented at the 41st European Society for Medical Oncology Congress
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