A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Effects of KW-3902 Injectable Emulsion on Heart Failure Signs and Symptoms and Renal Function in Subjects With Acute Heart Failure Syndrome and Renal Impairment Who Are Hospitalized for Volume Overload and Require Intravenous Diuretic Therapy

Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Effects of KW-3902 Injectable Emulsion on Heart Failure Signs and Symptoms and Renal Function in Subjects With Acute Heart Failure Syndrome and Renal Impairment Who Are Hospitalized for Volume Overload and Require Intravenous Diuretic Therapy

Completed
Phase of Trial: Phase III

Latest Information Update: 22 Sep 2016

At a glance

  • Drugs Rolofylline (Primary)
  • Indications Acute heart failure; Renal impairment
  • Focus Pharmacodynamics; Registrational; Therapeutic Use
  • Acronyms PROTECT-2
  • Sponsors NovaCardia
  • Most Recent Events

    • 22 Sep 2016 Results of a retrospective analysis from PROTECT-1 and PROTECT-2 studies published in the Heart.
    • 07 Oct 2010 Results from a pooled analysis of the PROTECT-1 and PROTECT-2 trials published in the New England Journal of Medicine [see also 700024421].
    • 16 Mar 2010 Results from a pooled analysis of the the PROTECT studies investigating the effects of treatment on renal function presented at the 59th Annual Scientific Session of the American College of Cardiology
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