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A Randomized, Double-Blind, Parallel-Group Study Conducted Under In-House Blinding Conditions to Determine the Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV) Associated With Moderately Emetogenic Chemotherapy (MEC)

Trial Profile

A Randomized, Double-Blind, Parallel-Group Study Conducted Under In-House Blinding Conditions to Determine the Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV) Associated With Moderately Emetogenic Chemotherapy (MEC)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 May 2022

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At a glance

  • Drugs Aprepitant (Primary) ; Dexamethasone; Fosaprepitant; Ondansetron
  • Indications Chemotherapy-induced nausea and vomiting
  • Focus Therapeutic Use
  • Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.
  • Most Recent Events

    • 17 Jun 2019 This trial has been completed in France, according to European Clinical Trials Database.
    • 26 May 2010 Primary endpoint 'Complete control of nausea and vomiting' and 'Patients with vomiting' has been met, according to a Merck media release.
    • 26 May 2010 Results have been published in Support Care Cancer 2010;18:423-431, according to a Merck media release.
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