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Interventional Management of Stroke Trial: A Phase III Clinical Trial Examining Whether a Combined Intravenous (IV) and Intra-Arterial (IA) Approach to Recanalization is Superior to Standard IV rt-PA (Activase) Alone When Initiated Within Three Hours of Acute Ischemic Stroke Onset.

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Trial Profile

Interventional Management of Stroke Trial: A Phase III Clinical Trial Examining Whether a Combined Intravenous (IV) and Intra-Arterial (IA) Approach to Recanalization is Superior to Standard IV rt-PA (Activase) Alone When Initiated Within Three Hours of Acute Ischemic Stroke Onset.

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 09 Feb 2023

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At a glance

  • Drugs Alteplase (Primary) ; Alteplase (Primary)
  • Indications Embolism and thrombosis; Stroke
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms IMS-III

    • Most Recent Events

    • 04 Jan 2023 Results (n=525) assessing to quantify the association between disabling neurological deficits and the EQ-5D dimension scores and the utility score in patients with ischemic stroke published in the Neurology
    • 01 May 2020 Results of secondary analysis of IMS-III and NINDS tPA trials presented at the 72nd Annual Meeting of the American Academy of Neurology
    • 21 Feb 2020 Results of pooled analysis of ALIAS I, II and IMS-III trials presented at the International Stroke Conference 2020
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