A Randomised, Double-Blind, Parallel Group, Phase 3, Efficacy and Safety Study of AZD6140 Compared With Clopidogrel for Prevention of Vascular Events in Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS) [PLATO- a Study of PLATelet Inhibition and Patient Outcomes].

Trial Profile

A Randomised, Double-Blind, Parallel Group, Phase 3, Efficacy and Safety Study of AZD6140 Compared With Clopidogrel for Prevention of Vascular Events in Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS) [PLATO- a Study of PLATelet Inhibition and Patient Outcomes].

Completed
Phase of Trial: Phase III

Latest Information Update: 15 Nov 2017

At a glance

  • Drugs Clopidogrel (Primary) ; Ticagrelor (Primary)
  • Indications Acute coronary syndromes; Cardiovascular disorders; Embolism and thrombosis
  • Focus Registrational; Therapeutic Use
  • Acronyms PLATO
  • Sponsors AstraZeneca
  • Most Recent Events

    • 15 Nov 2017 Results of PLATO substudy assessing fibrin clot properties and clinical outcomes, presented at the 90th Annual Scientific Sessions of the American Heart Association.
    • 16 Nov 2016 Results (n=5135) assessing Osteoprotegerin association With major bleeding and cardiovascular outcomes presented at the 89th Annual Scientific Sessions of the American Heart Association
    • 01 Jul 2016 Results of subgroup analysis (n=4020) published in the American Heart Journal
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