A Multicenter, Randomized, Double-Period, Double-Blind Study to Determine the Optimal Protocol for Treatment Initiation With Methotrexate and Adalimumab Combination Therapy in Patients With Early Rheumatoid Arthritis - OPTIMA.

Trial Profile

A Multicenter, Randomized, Double-Period, Double-Blind Study to Determine the Optimal Protocol for Treatment Initiation With Methotrexate and Adalimumab Combination Therapy in Patients With Early Rheumatoid Arthritis - OPTIMA.

Completed
Phase of Trial: Phase IV

Latest Information Update: 17 Jun 2017

At a glance

  • Drugs Adalimumab (Primary) ; Methotrexate
  • Indications Rheumatoid arthritis
  • Focus Therapeutic Use
  • Acronyms OPTIMA
  • Sponsors Abbott Laboratories
  • Most Recent Events

    • 17 Jun 2017 Results of long-term outcomes data from two studies (PREMIER and OPTIMA) presented at the 18th Annual Congress of the European League Against Rheumatism
    • 17 Jun 2017 Results of post hoc analysis assessing the insufficient response of Methotrexate and rapid radiographic progression (RRP) among pts with early RA, presented at the 18th Annual Congress of the European League Against Rheumatism
    • 17 Jun 2017 Results of post-hoc analysis identifying patient disease characteristics and early clinical responses which predict maintenance of low disease activity presented at the 18th Annual Congress of the European League Against Rheumatism
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