Phase II Study of Preoperative Radiation With Concurrent Capecitabine, Oxaliplatin and Bevacizumab Followed by Surgery and Postoperative 5-FU, Leucovorin, Oxaliplatin (FOLFOX) and Bevacizumab in Patients With Locally Advanced Rectal Cancer

Trial Profile

Phase II Study of Preoperative Radiation With Concurrent Capecitabine, Oxaliplatin and Bevacizumab Followed by Surgery and Postoperative 5-FU, Leucovorin, Oxaliplatin (FOLFOX) and Bevacizumab in Patients With Locally Advanced Rectal Cancer

Completed
Phase of Trial: Phase II

Latest Information Update: 13 Dec 2017

At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Rectal cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 25 Feb 2016 NCT reports trial status as active, no longer recruiting and results report as completed;kept as per results as it is the more reliable source.
    • 29 May 2015 Primary endpoint was not met (Pathologic Complete Response Rate) according to results presented at the 51st Annual Meeting of the American Society of Clinical Oncology.
    • 29 May 2015 5-year clinical outcome results were presented at the 51st Annual Meeting of the American Society of Clinical Oncology.
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