Phase II neoadjuvant chemotherapy trial in clinical stage II/III Her2Neu positive breast cancer with sequential doxorubicin and cyclophosphamide (AC) - docetaxel with concurrent dual EGFR [epidermal growth factor receptor] kinase blockade by GW572016 (lapatinib).

Trial Profile

Phase II neoadjuvant chemotherapy trial in clinical stage II/III Her2Neu positive breast cancer with sequential doxorubicin and cyclophosphamide (AC) - docetaxel with concurrent dual EGFR [epidermal growth factor receptor] kinase blockade by GW572016 (lapatinib).

Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2012

At a glance

  • Drugs Cyclophosphamide (Primary) ; Dexamethasone (Primary) ; Docetaxel (Primary) ; Doxorubicin (Primary) ; Filgrastim (Primary) ; Lapatinib (Primary) ; Pegfilgrastim (Primary) ; Trastuzumab (Primary)
  • Indications Breast cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 09 Mar 2011 Actual end date (Mar 2011) added as reported by ClinicalTrials.gov.
    • 09 Mar 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.
    • 25 Jan 2011 Additional lead trial investigator identified as reported by ClinicalTrials.gov.
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