A Phase I, open-label, 2-period, single-sequence, drug interaction study to assess steady-state plasma methadone enantiomer pharmacokinetics following co-administration of methadone QD with fosamprenavir 700mg BID + RTV [ritonavir] 100mg BID in opiate-dependent, HIV seronegative, adult subjects.

Trial Profile

A Phase I, open-label, 2-period, single-sequence, drug interaction study to assess steady-state plasma methadone enantiomer pharmacokinetics following co-administration of methadone QD with fosamprenavir 700mg BID + RTV [ritonavir] 100mg BID in opiate-dependent, HIV seronegative, adult subjects.

Completed
Phase of Trial: Phase I

Latest Information Update: 09 Mar 2010

At a glance

  • Drugs Fosamprenavir; Methadone; Ritonavir
  • Indications Opioid abuse
  • Focus Pharmacokinetics
  • Sponsors GlaxoSmithKline
  • Most Recent Events

    • 31 Jul 2007 New trial record.
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