A Phase I, open-label, 2-period, single-sequence, drug interaction study to assess steady-state plasma methadone enantiomer pharmacokinetics following co-administration of methadone QD with fosamprenavir 700mg BID + RTV [ritonavir] 100mg BID in opiate-dependent, HIV seronegative, adult subjects.
Phase of Trial: Phase I
Latest Information Update: 09 Mar 2010
At a glance
- Drugs Fosamprenavir; Methadone; Ritonavir
- Indications Opioid abuse
- Focus Pharmacokinetics
- Sponsors GlaxoSmithKline
- 31 Jul 2007 New trial record.