A Prospective, Randomized, Open-labelled, Multi-centre Trial Comparing the Safety and Efficacy of Ritonavir-boosted Aptivus (Tipranavir, TPV/r [ritonavir]) to That of Prezista (Darunavir, DRV/r) in Three-class (NRTI [nucleoside RT inhibitors], NNRTI, and PI [protease inhibitor]) Treatment-experienced Patients With Resistance to More Than One PI. POTENT: PrOspecTive EvaluatioN of Tipranavir vs. Darunavir in Treatment Experienced Patients.

Trial Profile

A Prospective, Randomized, Open-labelled, Multi-centre Trial Comparing the Safety and Efficacy of Ritonavir-boosted Aptivus (Tipranavir, TPV/r [ritonavir]) to That of Prezista (Darunavir, DRV/r) in Three-class (NRTI [nucleoside RT inhibitors], NNRTI, and PI [protease inhibitor]) Treatment-experienced Patients With Resistance to More Than One PI. POTENT: PrOspecTive EvaluatioN of Tipranavir vs. Darunavir in Treatment Experienced Patients.

Discontinued
Phase of Trial: Phase III

Latest Information Update: 28 Jan 2014

At a glance

  • Drugs Tipranavir (Primary) ; Darunavir; Ritonavir
  • Indications HIV-1 infections
  • Focus Pharmacogenomic; Therapeutic Use
  • Acronyms POTENT
  • Sponsors Boehringer Ingelheim Pharmaceuticals
  • Most Recent Events

    • 07 Jun 2017 Biomarkers information updated
    • 23 Oct 2012 Planned number of patients changed from 800 to 1040 as reported by European Clinical Trials Database.
    • 17 Dec 2009 Additional trial location [Bahamas, Thailand] identified as reported by ClinicalTrials.gov.
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