A Randomized Multicenter Double-Blind Group-Sequential Study to Evaluate the Efficacy Immunogenicity and Safety of a Single Dose of Merck Staphylococcus Aureus Vaccine (V710) in Adult Patients Scheduled for Cardiothoracic Surgery.

Trial Profile

A Randomized Multicenter Double-Blind Group-Sequential Study to Evaluate the Efficacy Immunogenicity and Safety of a Single Dose of Merck Staphylococcus Aureus Vaccine (V710) in Adult Patients Scheduled for Cardiothoracic Surgery.

Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 03 Dec 2016

At a glance

  • Drugs V-710 (Primary)
  • Indications Mediastinitis; Postoperative infections; Staphylococcal infections
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme
  • Most Recent Events

    • 03 Apr 2013 Primary endpoint 'Vaccine-protective-efficacy' has not been met.
    • 03 Apr 2013 Results published in JAMA: the Journal of the American Medical Association.
    • 11 Aug 2012 Additional trial locations added as reported by European Clinical Trials Database record.
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top