Trial Profile
A Single Arm Multicentre Phase II Study of Panitumumab in Combination With Irinotecan/5-fluorouracil/Leucovorin in Patients With Metastatic Colorectal Cancer.
Status:
Completed
Phase of Trial:
Phase II
Latest Information Update: 14 Oct 2021
Price :
$35
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At a glance
- Drugs Panitumumab (Primary) ; Fluorouracil; Folinic acid; Irinotecan
- Indications Adenocarcinoma; Colorectal cancer
- Focus Registrational; Therapeutic Use
- Sponsors Amgen
- 12 Jul 2019 Results of retrospective analysis investigating the effects of primary tumour location and early tumour shrinkage on trial outcomes published in the Drugs in R and D.
- 20 Jan 2018 Results of a post-hoc analysis assessing the impact of primary tumour location on outcomes in patients with RAS wild-type metastatic colorectal cancer undergoing first-line panitumumab plus FOLFIRI treatment, presented at the 2018 Gastrointestinal Cancers Symposium.
- 20 Oct 2016 Results of retrospective analysis assessing impact of tumour RAS/BRAF status in a first-line study of panitumumab in combination with FOLFIRI published in the British Journal of Cancer.