A multinational, randomized, double-blind study, comparing the efficacy of aflibercept once every 2 weeks versus placebo in patients with metastatic colorectal cancer (MCRC) treated with irinotecan/5-FU combination (FOLFIRI) after failure of an oxaliplatin based regimen.

Trial Profile

A multinational, randomized, double-blind study, comparing the efficacy of aflibercept once every 2 weeks versus placebo in patients with metastatic colorectal cancer (MCRC) treated with irinotecan/5-FU combination (FOLFIRI) after failure of an oxaliplatin based regimen.

Completed
Phase of Trial: Phase III

Latest Information Update: 21 Jan 2017

At a glance

  • Drugs Aflibercept (Primary) ; Fluorouracil; Folinic acid; Irinotecan
  • Indications Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms VELOUR
  • Sponsors Sanofi
  • Most Recent Events

    • 21 Jan 2017 Results (n=553) presented at the 2017 Gastrointestinal Cancers Symposium
    • 26 Dec 2015 Post hoc analysis results published in the Targeted Oncology.
    • 02 Jun 2015 Results presented at the 51st Annual Meeting of the American Society of Clinical Oncology.
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