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An Open-Label, Dose Escalation, Phase 1 Study of IXAZOMIB (MLN9708), a Second-Generation Proteasome Inhibitor, in Adult Patients With Advanced Nonhematologic Malignancies.

Trial Profile

An Open-Label, Dose Escalation, Phase 1 Study of IXAZOMIB (MLN9708), a Second-Generation Proteasome Inhibitor, in Adult Patients With Advanced Nonhematologic Malignancies.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Nov 2021

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At a glance

  • Drugs Ixazomib (Primary)
  • Indications Head and neck cancer; Non-small cell lung cancer; Prostate cancer; Soft tissue sarcoma; Squamous cell cancer
  • Focus Adverse reactions
  • Sponsors Millennium
  • Most Recent Events

    • 13 Mar 2017 Results (n=755) of pooled analysis of (C16001,C16002,C16003,C16004,C16005,C16007,C16008,C16010,C16013,TB-MC010034) ten studies assessing pharmacokinetic analysis of Ixazomib published in the Clinical Pharmacokinetics.
    • 18 Mar 2015 Results published in the Investigational New Drugs.
    • 22 Jun 2012 Actual patient number is 116 according to ClinicalTrials.gov.
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