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A Randomized Phase III Trial of CC-5013 (Lenalidomide, NSC-703813) and Low Dose Dexamethasone (LLD) Versus Bortezomib (PS-341, NSC-681239), Lenalidomide and Low Dose Dexamethasone (BLLD) for Induction, in Patients With Previously Untreated Multiple Myeloma Without an Intent for Immediate Autologous Stem Cell Transplant

Trial Profile

A Randomized Phase III Trial of CC-5013 (Lenalidomide, NSC-703813) and Low Dose Dexamethasone (LLD) Versus Bortezomib (PS-341, NSC-681239), Lenalidomide and Low Dose Dexamethasone (BLLD) for Induction, in Patients With Previously Untreated Multiple Myeloma Without an Intent for Immediate Autologous Stem Cell Transplant

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Feb 2024

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At a glance

  • Drugs Bortezomib (Primary) ; Dexamethasone; Lenalidomide
  • Indications Multiple myeloma
  • Focus Registrational; Therapeutic Use
  • Most Recent Events

    • 12 Dec 2023 Results (n=541) of a secondary post-hoc analysis of SWOG Studies S0777 and S1211 assessing impact of Dexamethasone dose reductions on post-induction outcomes in subset of patients who completed all eight 3-week cycles of induction presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 06 Jun 2023 Results presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 13 Dec 2022 Results (n=471) of post hoc analysis exploring possible treatment effect heterogeneity based on age, with a cutpoint of greater than 65 years, presented at the 64th American Society of Hematology Annual Meeting and Exposition
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