A Phase I Dose Escalation Study of LBH589 [panobinostat] in Combination With Imatinib Mesylate for Treatment of Patients With Chronic Myeloid Leukemia in Cytogenetic Remission With Residual BCR-ABL +Cells Detectably by Q-PCR [quantitative-polymerase chain reaction].

Trial Profile

A Phase I Dose Escalation Study of LBH589 [panobinostat] in Combination With Imatinib Mesylate for Treatment of Patients With Chronic Myeloid Leukemia in Cytogenetic Remission With Residual BCR-ABL +Cells Detectably by Q-PCR [quantitative-polymerase chain reaction].

Completed
Phase of Trial: Phase I

Latest Information Update: 10 Oct 2014

At a glance

  • Drugs Imatinib; Panobinostat
  • Indications Chronic myeloid leukaemia
  • Focus Adverse reactions; Biomarker
  • Most Recent Events

    • 07 Jun 2017 Biomarkers information updated
    • 01 Mar 2013 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 16 Jul 2012 Planned number of patients changed from 18 to 23 as reported by ClinicalTrials.gov.
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