Trial Profile
An Open-Label, Dose Escalation, Phase I Study of MLN4924, a Novel Inhibitor of Nedd8 Activating Enzyme, in Adult Patients With Lymphoma or Multiple Myeloma.
Status:
Completed
Phase of Trial:
Phase I
Latest Information Update: 06 Aug 2019
Price :
$35
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At a glance
- Drugs Pevonedistat (Primary)
- Indications Lymphoma; Multiple myeloma; Waldenstrom's macroglobulinaemia
- Focus Adverse reactions; Biomarker; Pharmacodynamics; Pharmacokinetics
- Sponsors Millennium
- 29 Jul 2019 A population pharmacokinetic analysis was conducted to quantify the impact of patient-specific and concurrent medication factors on pevonedistat pharmacokinetics using pooled data from 6 clinical studies ; results published in the British Journal of Clinical Pharmacology
- 11 Nov 2015 Results published in the Clinical cancer research: an official journal of the American Association for Cancer Research (n = 44).
- 01 Sep 2013 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.