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A Randomized, Double-Blind, Placebo-Controlled, Event-Driven Multicenter Study to Evaluate the Efficacy and Safety of Rivaroxaban in Subjects With a Recent Acute Coronary Syndrome

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Event-Driven Multicenter Study to Evaluate the Efficacy and Safety of Rivaroxaban in Subjects With a Recent Acute Coronary Syndrome

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Jan 2022

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At a glance

  • Drugs Rivaroxaban (Primary)
  • Indications Acute coronary syndromes; Cardiovascular disorders; Embolism and thrombosis; Myocardial infarction; Stroke
  • Focus Registrational; Therapeutic Use
  • Acronyms ATLAS-2-TIMI-51; ATLAS-ACS-2-TIMI-51
  • Sponsors Janssen Research & Development
  • Most Recent Events

    • 15 Nov 2021 Results of post hoc analysis assessing predictive and protective factors of early, late, and very late stent thrombosis presented at the American Heart Association Scientific Sessions 2021
    • 03 Aug 2021 Results of systematic review and meta-analysis fom COMMANDER HF, ATLAS ACS 2-TIMI 51 and COMPASS; evaluating efficacy and safety of rivaroxaban in patients with coronary artery disease, heart failure and sinus rhythm, published in the European Journal of Clinical Pharmacology
    • 17 May 2021 Results of Meta-Analysis from Atlas-ACS-2 TIMI-51, COMMANDER HF, COMPASS and VOYAGER PAD; assessing whether low-dose Rivaroxaban is associated with reduction in ischemic outcomes but with increased bleeding, presented at the 70th Annual Scientific Session of the American College of Cardiology
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