A Phase I Dose Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacokinetics and Neuropharmacodynamics of Temsirolimus With and Without Temozolomide in Patients With Primary or Metastatic Brain Tumors.

Trial Profile

A Phase I Dose Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacokinetics and Neuropharmacodynamics of Temsirolimus With and Without Temozolomide in Patients With Primary or Metastatic Brain Tumors.

Completed
Phase of Trial: Phase I

Latest Information Update: 28 Jul 2016

At a glance

  • Drugs Temsirolimus (Primary) ; Temozolomide
  • Indications Brain cancer; Cancer metastases; Solid tumours
  • Focus Adverse reactions; Pharmacodynamics
  • Most Recent Events

    • 09 Mar 2011 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 21 Nov 2008 New trial record.
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