Trial Profile
Phase I/Randomized Phase II Trial of Either Dasatinib or Placebo Combined With Standard Chemo-Radiotherapy for Newly Diagnosed Glioblastoma Multiforme (GBM)
Status:
Completed
Phase of Trial:
Phase I/II
Latest Information Update: 17 Feb 2020
Price :
$35
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At a glance
- Drugs Dasatinib (Primary) ; Temozolomide
- Indications Astrocytoma; Glioblastoma
- Focus Adverse reactions; Therapeutic Use
- 04 Feb 2020 Status changed from active, no longer recruiting to completed.
- 31 Jul 2015 Planned primary completion date changed from 1 Oct 2014 to 1 Oct 2015 as reported by ClinicalTrials.gov.
- 02 Jun 2015 The phase I results established the MTD and phase II dose of dasatinib to be 150 mg PO daily when given with temozolomide and radiotherapy, according to the abstract presented at ASCO 2015.