A Double-Blind, Randomized, Placebo-Controlled, 5-Period Crossover Study to Evaluate the Effects of a Single Dose of Losartan, a Single Dose of Isosorbide Mononitrate (ISMN), and Single Doses of Losartan + ISMN on Central Blood Pressure Measurements in Mildly Hypertensive Patients.

Trial Profile

A Double-Blind, Randomized, Placebo-Controlled, 5-Period Crossover Study to Evaluate the Effects of a Single Dose of Losartan, a Single Dose of Isosorbide Mononitrate (ISMN), and Single Doses of Losartan + ISMN on Central Blood Pressure Measurements in Mildly Hypertensive Patients.

Completed
Phase of Trial: Phase I

Latest Information Update: 09 Jun 2014

At a glance

  • Drugs Losartan (Primary) ; Isosorbide mononitrate
  • Indications Hypertension
  • Focus Pharmacodynamics
  • Sponsors Merck & Co
  • Most Recent Events

    • 28 Jul 2009 New trial record
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