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Randomized Three Arm Phase III Trial on Induction Treatment With a Fluoropyrimidine-, Oxaliplatin- and Bevacizumab-based Chemotherapy for 24 Weeks Followed by Maintenance Treatment With a Fluoropyrimidine and Bevacizumab vs. Bevacizumab Alone vs. no Maintenance Treatment and Reinduction in Case of Progression for First-line Treatment of Patients With Metastatic Colorectal Cancer.

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Trial Profile

Randomized Three Arm Phase III Trial on Induction Treatment With a Fluoropyrimidine-, Oxaliplatin- and Bevacizumab-based Chemotherapy for 24 Weeks Followed by Maintenance Treatment With a Fluoropyrimidine and Bevacizumab vs. Bevacizumab Alone vs. no Maintenance Treatment and Reinduction in Case of Progression for First-line Treatment of Patients With Metastatic Colorectal Cancer.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 25 Apr 2022

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine; Fluoropyrimidine derivatives; Fluorouracil; Folic acid; Oxaliplatin
  • Indications Colorectal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 20 Jul 2018 Results published in the European Journal of Cancer
    • 05 Jun 2018 Results presented at the 54th Annual Meeting of the American Society of Clinical Oncology
    • 06 Jun 2017 Results of pooled analysis of AIO KRK 0207 and RO91 trials presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
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