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A randomized, double-blind, placebo-controlled study to assess the efficacy of tocilizumab (TCZ) + non-biological DMARD in reducing synovitis as measured by magnetic resonance imaging (MRI) at 12 weeks after initiation of treatment in patients with moderate to severe rheumatoid arthritis (RA) with inadequate response to non-biological DMARDs.

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Trial Profile

A randomized, double-blind, placebo-controlled study to assess the efficacy of tocilizumab (TCZ) + non-biological DMARD in reducing synovitis as measured by magnetic resonance imaging (MRI) at 12 weeks after initiation of treatment in patients with moderate to severe rheumatoid arthritis (RA) with inadequate response to non-biological DMARDs.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Tocilizumab (Primary) ; Disease-modifying antirheumatics
  • Indications Rheumatoid arthritis
  • Focus Therapeutic Use
  • Acronyms PORTRAIT
  • Sponsors Roche

    • Most Recent Events

    • 21 Apr 2012 Official Title amended as reported by European Clinical Trials Database record.
    • 21 Apr 2012 Planned end date (30 Sep 2011) added as reported by European Clinical Trials Database.
    • 21 Apr 2012 Status changed from recruiting to completed as reported by European Clinical Trials Database.
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