A Phase 1-2 Dose-Escalation and Safety Study of ADXS31-142 Alone and of ADXS31-142 in Combination With Pembrolizumab (MK-3475) in Patients With Previously Treated Metastatic Castration-Resistant Prostate Cancer

Trial Profile

A Phase 1-2 Dose-Escalation and Safety Study of ADXS31-142 Alone and of ADXS31-142 in Combination With Pembrolizumab (MK-3475) in Patients With Previously Treated Metastatic Castration-Resistant Prostate Cancer

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 02 Aug 2017

At a glance

  • Drugs ADXS 31142 (Primary) ; Pembrolizumab (Primary)
  • Indications Prostate cancer
  • Focus Adverse reactions; First in man
  • Acronyms KEYNOTE-046
  • Sponsors Advaxis
  • Most Recent Events

    • 02 Aug 2017 According to an Advaxis media release, two poster presentations featuring preliminary immune correlative data from this trial will were selected for presentation at the third annual CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival.
    • 13 Jun 2017 According to an Advaxis media release, data from this trial presented at annual Investor & Analyst Day.
    • 13 Jun 2017 According to an Advaxis media release, data from this trial have been submitted for presentation at the CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference 2017.
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