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An Efficacy and 2-Year Safety Study of Open-label Rosuvastatin in Children and Adolescents (Aged From 6 to Less Than 18 Years) With Familial Hypercholesterolaemia.

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Trial Profile

An Efficacy and 2-Year Safety Study of Open-label Rosuvastatin in Children and Adolescents (Aged From 6 to Less Than 18 Years) With Familial Hypercholesterolaemia.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Jul 2017

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At a glance

  • Drugs Rosuvastatin (Primary)
  • Indications Hypercholesterolaemia
  • Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics; Registrational; Therapeutic Use
  • Acronyms CHARON
  • Sponsors AstraZeneca

    • Most Recent Events

    • 07 Jun 2017 Results (n=198) assessing the efficacy of Rosuvastatin on carotid intima-media thickness in children with heterozygous familial hypercholesterolemia, published in the Circulation
    • 21 Sep 2015 Results of population pharmacokinetics of rosuvastatin in pediatric patients from two studies published in the European Journal of Clinical Pharmacology.
    • 31 Mar 2014 Results for the effect of rosuvastatin on carotid intima media thickness presented at the 63rd Annual Scientific Session of the American College of Cardiology.
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