A Randomized, Placebo-controlled, Two-period, Two-treatment, Two Sequence, Cross-over Pharmacodynamic and Pharmacokinetic Interaction Study After 5-days Repeated Oral Doses of Clopidogrel (300 mg Loading Dose Followed by 75 mg/Day) Alone or Given Concomitantly With Pantoprazole 80 mg/Day in Healthy Male Subjects.

Trial Profile

A Randomized, Placebo-controlled, Two-period, Two-treatment, Two Sequence, Cross-over Pharmacodynamic and Pharmacokinetic Interaction Study After 5-days Repeated Oral Doses of Clopidogrel (300 mg Loading Dose Followed by 75 mg/Day) Alone or Given Concomitantly With Pantoprazole 80 mg/Day in Healthy Male Subjects.

Completed
Phase of Trial: Phase I

Latest Information Update: 14 Dec 2011

At a glance

  • Drugs Clopidogrel; Pantoprazole
  • Indications Acute coronary syndromes; Angina pectoris; Atherosclerosis; Cardiovascular disorders; Duodenal ulcer; Embolism and thrombosis; Erosive oesophagitis; Gastric ulcer; Gastritis; Gastro-oesophageal reflux; Heartburn; Helicobacter infections; Ischaemic heart disorders; Myocardial infarction; Peptic ulcer; Peripheral arterial occlusive disorders; Stroke; Unstable angina pectoris; Zollinger-Ellison syndrome
  • Focus Pharmacodynamics; Pharmacokinetics
  • Sponsors Sanofi
  • Most Recent Events

    • 28 Aug 2010 Results were presented at the Annual Congress of the European Society of Cardiology.
    • 27 Aug 2010 Trial phase changed from IV to I as reported by ClinicalTrials.gov.
    • 01 Jun 2010 New trial record
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