A Phase 1, Randomized, Double-blind, Placebo-controlled, Ascending Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181 in Healthy Subjects and Subjects With Mild to Moderate Ulcerative Colitis.

Trial Profile

A Phase 1, Randomized, Double-blind, Placebo-controlled, Ascending Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181 in Healthy Subjects and Subjects With Mild to Moderate Ulcerative Colitis.

Discontinued
Phase of Trial: Phase I

Latest Information Update: 06 May 2014

At a glance

  • Drugs Abrilumab (Primary) ; Abrilumab (Primary)
  • Indications Ulcerative colitis
  • Focus Adverse reactions
  • Most Recent Events

    • 06 May 2014 Results published in the British Journal of Clinical Pharmacology.
    • 24 Jul 2013 Status changed from recruiting to discontinued as reported by ClinicalTrials.gov.
    • 18 May 2013 Interim results of a combined analysis of this trial and trial 700194409 presented at the Digestive Disease Week 2013.
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